Disopyramide: Although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome?

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Peritoneal adhesion: it can be life-threatening, and life-saving

BACKGROUND The inevitable post-inflammatory fibrosis and adhesion often compromises future treatment in peritoneal dialysis patients. Here, we describe a patient who experienced an unusual form of peritoneal adhesion that made her give up peritoneal dialysis. However, its unique pattern also saved her from infection caused by bowel perforation. CASE PRESENTATION The female patient discontinue...

متن کامل

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

BACKGROUND The congenital long-QT syndrome (LQTS) is caused by mutations on several genes, all of which encode cardiac ion channels. The progressive understanding of the electrophysiological consequences of these mutations opens unforeseen possibilities for genotype-phenotype correlation studies. Preliminary observations suggested that the conditions ("triggers") associated with cardiac events ...

متن کامل

Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals.

OBJECTIVES This study was designed to assess the clinical course and to identify risk factors for life-threatening events in patients with long-QT syndrome (LQTS) with normal corrected QT (QTc) intervals. BACKGROUND Current data regarding the outcome of patients with concealed LQTS are limited. METHODS Clinical and genetic risk factors for aborted cardiac arrest (ACA) or sudden cardiac deat...

متن کامل

Long QT syndrome and life threatening arrhythmia in a newborn: molecular diagnosis and treatment response.

Intrauterine and neonatal manifestations of congenital long QT syndrome are associated with a high cardiac risk, particularly when atrioventricular block and excessive QT prolongation (> 600 ms(1/2)) are present. In a female newborn with these features, treatment with propranolol and mexiletine led to complete reduction of arrhythmia that was maintained 1.5 years later. High throughput genetic ...

متن کامل

Relation between bradycardia dependent long QT syndrome and QT prolongation by disopyramide in humans.

BACKGROUND Recent molecular biological investigations have identified abnormal genes in familial forms of long QT syndrome, but in bradycardia dependent acquired long QT syndrome, no such genetic abnormality has yet been identified. OBJECTIVE To investigate the relation between the responses of QT interval to pacing change and to disopyramide. METHODS This study included 13 patients with br...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Molecular and Cellular Cardiology

سال: 2006

ISSN: 0022-2828

DOI: 10.1016/j.yjmcc.2006.06.070